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Cruises to South America

See all South America sailings →
◆Which ship is right for you◆
Top of the class
Seven Seas Grandeur
This Small ship from Regent Seven Seas Cruises leads every South America vessel on our grade.
Travelers' favorite
4.6
Viking Jupiter
Highest review score in the region: 4.6/5 across 537 published reviews.
◆Best ships sailing South America◆
#2
Seven Seas Grandeur
Regent Seven Seas Cruises · Ultra-luxury
Small ship (744 guests) · new in 2023 · Great food · Recently refreshed · Ultra-luxury
Vessel
4.1Reviews
#5
Viking Jupiter
Viking Ocean Cruises · Luxury
Mid-size ship (930 guests) · refit 2023 · Great food · Recently refreshed · Adults-only
Vessel
4.6Reviews
#11
Silver Shadow
Silversea Cruises · Ultra-luxury
Small ship (392 guests) · refit 2019 · Great food · Ultra-luxury
Vessel
3.8Reviews
#14
Seabourn Quest
Seabourn Cruise Line · Ultra-luxury
Small ship (450 guests) · refit 2026 · Great food · Recently refreshed · Ultra-luxury
Vessel
4.1Reviews
#18
Seven Seas Voyager
Regent Seven Seas Cruises · Ultra-luxury
Small ship (698 guests) · refit 2016 · Ultra-luxury
Vessel
3.6Reviews
#19
Seven Seas Mariner
Regent Seven Seas Cruises · Ultra-luxury
Small ship (700 guests) · refit 2025 · Great food · Recently refreshed · Great for families
Vessel
3.8Reviews
#29
MSC Divina
MSC Cruises · Contemporary
Large resort ship (3,502 guests) · refit 2025 · Recently refreshed
Vessel
3.4Reviews
#31
MSC Seaview
MSC Cruises · Contemporary
Large resort ship (4,132 guests) · refit 2023 · Recently refreshed
Vessel
3.1Reviews
#41
MSC Splendida
MSC Cruises · Contemporary
Large resort ship (3,900 guests) · refit 2024 · Recently refreshed
Vessel
3.3Reviews
#43
Majestic Princess
Princess Cruises · Premium
Large resort ship (3,560 guests) · refit 2025 · Recently refreshed
Vessel
3.6Reviews
#52
Celebrity Equinox
Celebrity Cruises · Premium
Large resort ship (2,850 guests) · refit 2019
Vessel
4.3Reviews
#54
MSC Virtuosa
MSC Cruises · Contemporary
Large resort ship (4,842 guests) · refit 2025 · Recently refreshed
Vessel
2.9Reviews
#76
MSC Musica
MSC Cruises · Contemporary
Large resort ship (2,550 guests) · refit 2024 · Recently refreshed
Vessel
3.6Reviews
#93
MS Zuiderdam
Holland America Line · Premium
Large resort ship (1,916 guests) · refit 2025 · Recently refreshed
Vessel
3.9Reviews
#118
MS Nieuw Amsterdam
Holland America Line · Premium
Large resort ship (2,106 guests) · refit 2023 · Recently refreshed
Vessel
3.8Reviews
◆Ports you’ll visit◆
Long Beach (Los Angeles)
At Sea
Acapulco
Crossing The Equator
Manta
Callao (Lima)
Coquimbo (La Serena)
San Antonio (Santiago)
Cruise Darwin Channel
Cruise Chilean Fjords
Cruise Amalia Glacier
Cruise Strait of Magellan
◆When to go◆
Nov 202613 sailingsDec 202657 sailingsJan 202759 sailingsOct 20277 sailingsJan 202811 sailings2027-123 sailings2028-032 sailings2028-026 sailingsFeb 202757 sailings2029-023 sailings2027-111 sailingsFeb 20286 sailings2027-016 sailingsDec 20277 sailingsMar 20284 sailings2026-122 sailingsOct 20283 sailings2027-023 sailingsMar 202741 sailingsApr 20271 sailingsNov 20273 sailings2027-031 sailings2028-017 sailings2029-011 sailings
◆Common questions◆
How long are South America cruises?

The South America sailings CruiseIndex tracks run 3 to 126 nights.

Which ports do South America cruises visit?

Tracked South America itineraries call at Long Beach (Los Angeles), At Sea, Acapulco, Crossing The Equator, Manta and Callao (Lima).

What is the best cruise ship in South America?

Seven Seas Grandeur (Regent Seven Seas Cruises) currently holds the region's top Vessel Class grade, #2 in our fleet-wide ranking.

More cruise guidesAustralia & New ZealandAsiaSouth PacificCaribbeanBahamasMexicoCanada & New EnglandBermudaMediterraneanPanama CanalAlaskaHawaiiTranspacificTransatlanticEuropeGalapagosPacific CoastWorld VoyagesIndian OceanCanary IslandsAfricaMiddle EastCentral America
Lines sailing South AmericaCarnival Cruise LineCelebrity CruisesHolland America LineMSC CruisesNorwegian Cruise LinePrincess CruisesRegent Seven Seas CruisesViking Ocean Cruises

Vessel Class and Review Score scores are live and real. Fares shown on sailing pages are preview samples until the live fare feed arrives.